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United States of America 🇺🇸

The Defense Threat Reduction Agency (DTRA) has issued a Broad Agency Announcement to solicit strategic research on future challenges related to weapons of mass destruction (WMD) over the next five to ten years. The solicitation, covering Fiscal Years 2025–2029, seeks analytical studies, policy analyses, and international dialogue facilitation that anticipate how nuclear, chemical, biological, and emerging technologies may be developed or employed by adversaries, and how such capabilities could impact U.S. deterrence, crisis prevention, and conflict‑resolution efforts. The research is intended to inform DTRA’s dual mission as a Defense Agency—supporting strategic policies to reduce global WMD threats—and a Combat Support Agency—identifying and fielding responsive solutions for Joint Staff and Combatant Commands.

Specifically, the initiative invites work that explores new or enhanced WMD materials, delivery mechanisms, or technologies that could increase the lethality or persistence of existing threats. Studies should assess the implications for U.S. allies and partners, providing timely, credible insights and actionable recommendations on deterrence, risk reduction, arms control, and escalation management. The solicitation encourages engagement in Track 1.5 and 2 international dialogues to broaden the analytical base and strengthen cross‑government collaboration.

Eligible work must conform to the NAICS codes listed in the announcement, including 54169 (Other Scientific and Technical Consulting Services), 54171 (Research and Development in Physical, Engineering, and Life Sciences), and related codes for nanotechnology, biotechnology, social sciences, and space research. All proposals must align with these classification requirements.

The Defense Threat Reduction Agency is issuing a Broad Agency Announcement to solicit strategic research addressing the future trajectory of weapons of mass destruction, specifically focusing on threats that may emerge or intensify within the next five to ten years. The solicitation invites research that examines nuclear, chemical, and biological weapon development, the materials, methodologies, and technologies that could enable new or amplified WMD capabilities, and the implications of such threats for deterrence, crisis prevention, risk reduction, arms control, and strategic competition. Work is expected to generate timely, credible, and actionable insights that inform the agency’s policy development and operational responses, and to contribute to the broader U.S. defense posture against CBRN‑armed adversaries.

The research portfolio encompasses analytical studies, international dialogues, and interdisciplinary investigations that may involve scientific, engineering, and social science perspectives. Eligible research activities may include laboratory and simulation work, field studies, policy analysis, and stakeholder engagement initiatives, all conducted under the broader framework of Defense Threat Reduction Agency priorities. Studies are required to align with the Service’s mission of providing forward‑looking counter‑WMD solutions, reinforcing deterrence, and supporting Joint Staff and Combatant Command operational needs. Research must adhere to the specified NAICS codes and DoD R&D standards.

The Federal Highway Administration Office of Infrastructure Research and Development is issuing a Broad Agency Announcement to solicit research white papers and proposals that advance next‑generation, low‑carbon binder technologies for concrete used in bridge and highway infrastructure. The solicitation, identified as BAA 693JJ3‑24‑BAA‑0003, calls for innovative solutions that can be benchmarked against an industrially produced Class A concrete with a 28‑day compressive strength of 4,000 psi, enabling the agency to accelerate the deployment of sustainable materials in national infrastructure projects. The research effort will be integrated within the FHWA’s Bridge Engineering Research Team’s program areas of Structural Steel, Structural Concrete, Geotechnical Structures, and Bridge Hydraulics, aligning with FHWA’s strategic priorities in safety, economic competitiveness, climate resilience, and transformative innovation.

Proposals must demonstrate that the candidate binder technologies—such as geopolymers, carbon‑atable minerals, recycled supplementary cementitious materials, and novel binder chemistries—meet or surpass the performance criteria specified by AASHTO LRFD Bridge Design Specifications, including strength, flexural, axial, shear, development length, fatigue, deflection, corrosion, freeze‑thaw, salt attack, and sulfate resistance limit states. Each submission must provide estimated embodied CO₂e per cubic meter, justified through an ISO 21930‑conformant Type III environmental product declaration or a life‑cycle assessment, and indicate the applicable technical specifications (e.g., AASHTO M85, ASTM C618‑23). The final requirement is that benchmarked low‑carbon binders satisfy the defined limit‑state performance metrics and provide documented embodied carbon estimates adhering to ISO 21930.

The Corrigendum-Health Science Futures (HSF) Mission Office Innovative Solutions Opening (ISO) is a solicitation aimed at obtaining innovative research‑development, healthcare service, and experimental development solutions that advance the ARPA‑H Health Science Futures mission. The HSF mission seeks to eliminate scientific and technological barriers to future healthcare by fostering disease‑agnostic research programs with the potential for translational real‑world impact. The ISO solicits solution summaries, followed by full proposals, that align with this ambitious directive.

Proposals submitted under this ISO involve cutting‑edge R&D services and experimental development initiatives that are intended to break new ground in the physical, engineering, and life sciences. The procurement focuses on projects that can be translated into tangible healthcare improvements and are expected to generate breakthroughs that can be applied across a broad range of medical challenges. Proposers are encouraged to provide detailed summaries of their scientific approach and a clear plan for translating laboratory insights into real‑world solutions.

All submissions must satisfy updated administrative and technical requirements, including compliance with conflict‑of‑interest and research security disclosures, adherence to revised intellectual property assertion guidelines, and updated human and animal subjects research and biosecurity protocols. The cost proposals must incorporate the newly defined burdened labor rates, increase the material documentation threshold to $10,000, and acknowledge that profit/fee is presumed inapplicable unless explicitly stated.

The Advanced Research Projects Agency for Health’s Resilient Systems Office (RSO) is issuing an Innovative Solutions Opening to solicit advanced health‑research and development proposals. The opportunity focuses on identifying and developing cutting‑edge technologies that address persistent gaps in the quality, efficacy, and consistent availability of care across the healthcare and public‑health landscape. Proposals are expected to demonstrate how the proposed solutions will meet the RSO’s systemic challenge objectives and advance the agency’s mission of building resilient health systems.

This solicitation specifically calls for health research and development services, health‑care services, and experimental development projects. Awardees will be engaged in research activities in the physical, engineering, and life sciences (excluding nanotechnology and biotechnology) and will be expected to deliver innovative deliverables that strengthen the resilience and effectiveness of healthcare delivery. The procurement aligns with the RSO’s priority areas of addressing public‑health challenges through technology‑driven research and development.

Amendments to the solicitation update administrative and cost‑proposal documentation, introducing new definitions for labor rates, consolidating intellectual‑property data assertions, and raising the unit‑cost threshold for supporting documentation from $5,000 to $10,000. All submissions must comply with the updated administrative, IP, and cost‑proposal guidelines and meet the specified unit‑cost threshold for materials and equipment.